Kunitada Shimotohno Selected Research

MicroRNAs (MicroRNA)

4/2021	Identification of microRNA associated with the elimination of hepatitis C virus genotype 1b by direct-acting antiviral therapies.
1/2020	Role of microRNA-210-3p in hepatitis B virus-related hepatocellular carcinoma.
8/2018	Circulating microRNA-636 is associated with the elimination of hepatitis C virus by ombitasvir/paritaprevir/ritonavir.
1/2011	The progression of liver fibrosis is related with overexpression of the miR-199 and 200 families.
10/2010	Hepatic microRNA expression is associated with the response to interferon treatment of chronic hepatitis C.

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Kunitada Shimotohno Research Topics

Disease

38	Infections 01/2022 - 05/2002
12	Virus Diseases (Viral Diseases) 01/2022 - 05/2005
8	Hepatocellular Carcinoma (Hepatoma) 04/2021 - 11/2006
8	T-Cell Leukemia (Leukemia, T Cell) 12/2008 - 10/2002
5	Chronic Hepatitis C 02/2020 - 04/2008
5	Neoplasms (Cancer) 01/2020 - 06/2002
5	Hepatitis C 11/2018 - 01/2004
4	Inflammation (Inflammations) 09/2014 - 05/2002
3	Chronic Hepatitis B 01/2022 - 01/2017
3	Hepatitis B 01/2022 - 01/2020
3	Chronic Hepatitis (Chronic Active Hepatitis) 07/2011 - 10/2004
3	Liver Diseases (Liver Disease) 07/2011 - 11/2003
2	COVID-19 10/2021 - 10/2020
2	Cardiovascular Diseases (Cardiovascular Disease) 05/2021 - 11/2018
2	Hepatitis 01/2021 - 01/2014
2	Bites and Stings (Sting) 12/2019 - 02/2019
2	Carcinogenesis 09/2008 - 06/2002
1	Viremia 01/2022
1	Hypertension (High Blood Pressure) 05/2021
1	Obesity 05/2021
1	Chronic Renal Insufficiency 05/2021
1	Type 2 Diabetes Mellitus (MODY) 10/2014
1	Hyperplasia 09/2014
1	Cryoglobulinemia 08/2014
1	Non-Hodgkin Lymphoma (Lymphosarcoma) 08/2014

Drug/Important Bio-Agent (IBA)

13	Antiviral Agents (Antivirals)IBA 01/2022 - 01/2007
11	Proteins (Proteins, Gene)FDA Link 01/2022 - 11/2003
9	InterferonsIBA 02/2019 - 11/2003
7	Small Interfering RNA (siRNA)IBA 01/2022 - 01/2004
6	RNA (Ribonucleic Acid)IBA 12/2021 - 07/2003
5	MicroRNAs (MicroRNA)IBA 04/2021 - 10/2010
5	sodium-bile acid cotransporterIBA 12/2020 - 11/2015
3	CytokinesIBA 12/2021 - 07/2013
3	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 10/2021 - 10/2020
3	Circular DNAIBA 01/2021 - 01/2016
3	DNA (Deoxyribonucleic Acid)IBA 07/2018 - 07/2006
3	Interferon-alpha (Interferon Alfa)IBA 01/2017 - 04/2008
3	Ribavirin (Virazole)FDA LinkGeneric 01/2011 - 04/2008
3	tax Gene Products (tax Gene Product)IBA 09/2008 - 09/2007
2	LuciferasesIBA 01/2022 - 12/2021
2	Monoclonal AntibodiesIBA 01/2022 - 12/2020
2	Amino Acids FDA Link 01/2022 - 01/2021
2	Hepatitis B e AntigensIBA 01/2021 - 07/2018
2	Pharmaceutical PreparationsIBA 02/2020 - 09/2018
2	Biomarkers (Surrogate Marker)IBA 01/2020 - 08/2018
2	A-factor (Streptomyces)IBA 12/2019 - 07/2011
2	Hepatitis B virus P proteinIBA 01/2018 - 01/2017
2	Messenger RNA (mRNA)IBA 01/2017 - 07/2013
2	nanolucIBA 01/2017 - 11/2015
2	Interferon Type IIBA 08/2014 - 01/2011
2	Cyclosporine (Ciclosporin)FDA LinkGeneric 12/2012 - 01/2007
2	NF-kappa B (NF-kB)IBA 04/2005 - 05/2002
2	Transcription Factors (Transcription Factor)IBA 04/2005 - 12/2004
2	LigandsIBA 12/2004 - 07/2004
2	beta CateninIBA 09/2004 - 06/2002
2	Subgenomic RNAIBA 07/2003 - 05/2002
2	Oncogene Proteins (Oncogene Protein)IBA 03/2003 - 10/2002
1	KinesinsIBA 01/2022
1	Bexarotene (LGD1069)FDA Link 01/2022
1	Bile Acids and Salts (Bile Acids)IBA 01/2022
1	Alitretinoin FDA Link 01/2022
1	myrcludex-BIBA 01/2022
1	Peptides (Polypeptides)IBA 01/2022
1	Immunoglobulin G (IgG)IBA 01/2022
1	pgRNAIBA 12/2021
1	Basic-Leucine Zipper Transcription FactorsIBA 12/2021
1	TrypsinIBA 05/2021
1	elbasvirIBA 04/2021
1	daclatasvirIBA 04/2021
1	asunaprevirIBA 04/2021
1	grazoprevirIBA 04/2021
1	OligonucleotidesIBA 04/2021
1	Isoleucine (L-Isoleucine)FDA Link 01/2021
1	Membrane Proteins (Integral Membrane Proteins)IBA 01/2021
1	Leucine (L-Leucine)FDA Link 01/2021
1	EpitopesIBA 12/2020
1	ErbB Receptors (EGF Receptor)IBA 01/2020
1	Epidermal Growth Factor (EGF)IBA 01/2020
1	Ligases (Synthetase)IBA 02/2019
1	cyclic guanosine monophosphate-adenosine monophosphateIBA 02/2019
1	Interferon LambdaIBA 02/2019
1	Interleukin-6 (Interleukin 6)IBA 02/2019
1	Protein Isoforms (Isoforms)IBA 11/2018
1	Apolipoproteins E (ApoE)IBA 11/2018
1	Antimalarials (Antimalarial Agents)IBA 09/2018
1	Untranslated RNA (Noncoding RNA)IBA 08/2018
1	AntigensIBA 07/2018
1	Hepatitis B Surface Antigens (HBsAg)FDA Link 07/2018
1	Alanine Transaminase (SGPT)IBA 07/2018
1	glabridinIBA 05/2018
1	tirbanibulinIBA 01/2017
1	src-Family KinasesIBA 01/2017
1	Long Noncoding RNAIBA 01/2016
1	Apolipoproteins B (ApoB)IBA 10/2015
1	Glucose (Dextrose)FDA LinkGeneric 10/2014
1	Viral ProteinsIBA 10/2014
1	Trans-Activators (Trans-Acting Factor)IBA 10/2014
1	Antigen-Antibody Complex (Immune Complex)IBA 08/2014

Therapy/Procedure

9	Therapeutics 04/2021 - 07/2004
1	Immunotherapy 03/2020